Two new aryltetralin-type lignans, isopodophyllotoxin 79-O-b-D-glucopyranosyl-(1®6)-b-D-glucopyranoside (1) and 4-demethyl-picropodophyllotoxin 79-O-b-D-glucopyranoside (2), along with eight known podophyllotoxin derivatives: 4-demethyl-podophyllotoxin 79-O-b-D-glucopyranoside (3), podophyllotoxin 79-O-b-D-glucopyranoside (4), deoxypodophyllotoxin (5), picropodophyllotoxin (6), podophyllotoxin (7), 4-demethyl-picropodophyllotoxin (8), 4-demethyl-podophyllotoxin (9), and 4-demethyl-deoxypodophyllotoxin (10), were isolated from the roots and rhizomes of Sinopodophyllum emodi (WALL.) YING (Berberidaceae). Their structures were identified based on NMR spectral data and chemical evidence.