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李梦龙

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期刊论文

Analyzing functional similarity of protein sequences with discrete wavelet transform

李梦龙Zhi-ning Wena Ke-long Wanga Meng-long Liab Fu-sheng Nieb Yi Yangc

Computational Biology and Chemistry 29(2005)220-228,-0001,():

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摘要/描述

This paper applies discrete wavelet transform (DWT) with various protein substitution models to find functional similarity of proteins with low identity. A new metric, 'S' function, based on the DWT is proposed to measure the pair-wise similarity. We also develop a segmentation technique, combined with DWT, to handle long protein sequences. The results are compared with those using the pair-wise alignment and PSI-BLAST.

【免责声明】以下全部内容由[李梦龙]上传于[2009年05月12日 10时51分07秒],版权归原创者所有。本文仅代表作者本人观点,与本网站无关。本网站对文中陈述、观点判断保持中立,不对所包含内容的准确性、可靠性或完整性提供任何明示或暗示的保证。请读者仅作参考,并请自行承担全部责任。

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