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期刊论文
Micronuclei induced by municipal landfill leachate in mouse bone marrow cells in vivo
Environmental Research 95(2004)77-81,-0001,():
The induction of micronuclei (MN) in polychromatic erythrocytes (PCE) of mouse bone marrow by municipal landfill leachate was studied in vivo. Results showed that mouse exposure via drinking water containing various concentrations of leachate caused asignificant increase of MN frequencies in a concentration (Chemical oxygen demand measured with potassium dichromate oxidation, CODCr)-ependent manner. MN induction in female and male mice was different at higher concentrations. This implies that leachate is a genotoxic agent in mammalian cells and that exposure to leachate in an aquatic environment may pose a potential genotoxic risk to human beings.
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