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期刊论文

Ectopic Osteogenesis of Bone Marrow Stromal Cells loading in Hydroxyapatite/β-Tricalcium Phosphate

田卫东Yunfeng Lin Ling Wu Lei Liu Ju Qiao Wei Jing Weidong Tiana

Key Engineering Materials Vols. 330-332 (2007) pp. 1109-1112,-0001,():

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摘要/描述

This study was to determine the ectopic osteogenic ability of BMSCs in combination with a scaffolding material comprising hydroxyapatite and β-tricalcium phosphate matrix (HA/β-TCP). BMSCs were obtained from the SD rats and induced to osteogenesis. Then these induced cells were seeded into HA/β-TCP and the constructs were auto-implanted subcutaneously for up to 12 weeks. Histological analysis, immunostaing, RT-PCR and transmission electron microscopy of the retrieved specimens at various intervals showed obvious trends of ectopic bone formation with obvious alteration of cellular phenotype.

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