The interaction and coalescence of multiple flaws will significantly influence the service life of components. In this paper, the interaction of two identical semi-elliptical cracks in a finite thickness plate subjected to the remote tension is investigated. The results indicated that interaction of multiple cracks is different between the time-dependent fracture characterized by C*-integral and linear elastic fracture noted by SIF. The magnifying factors of creep fracture are obviously larger than that of the linear elastic fracture cases. Therefore, the current interaction and coalescence rule developed from linear elastic fracture analysis may lead to a non-conservative result when it is used in the assessment of creep crack. At the end, an empirical equation is developed based on the numerical results.