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杨铭
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引用
期刊论文
Synthesis and Biological Evaluation of DNA Targeting Flexible Side-Chain Substituted β-Carboline Derivatives
Bioorganic & Medicinal Chemistry Letters 11(2001)437-441，-0001，（）：
A series of 3-substituted-β-carboline derivatives was synthesized from L-tryptophan. The intercalating binding mode of these compounds with DNA, the effects of the flexible alkylamine side chain on the intercalating a bility and their antitumor activity were studied, which agreed well with the molecular modeling results.
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