Selective bromination of toluidines and cresols with N-bromosuccinimide
首发时间:2013-12-26
Abstract:Using N-bromosuccinimide (NBS) as a convenientbromine source, bromination of toluidine and cresols was studied systematically to clarify the underlying mechanism and the orientation effect. Based on this methodology, several potential AChE inhibtors i.e. 3-bromo-2-methoxy-5-methyl-9H-carbazole, 3,6-dibromo-2-meth-oxy-5- methyl- 9H-carbazole, and 5-(bromomethyl)- 2-methoxy-9-(phenylsulfonyl)carbazole were synthesized.
keywords: Medicinal Chemistry Bromination N-bromosuccinimide Toluidine Cresol
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