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长期从事海洋生物资源的综合开发利用及海洋药物与食品工程教学和科研工作。
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通信地址:青岛市鱼山路5号中国海洋大学校长办公室
邮编:266003
E-mail:hsguan@mail.ocu.edu.cn
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  • 创建:2005-03-11
  • 浏览:9770
  • 论文下载:7841
个人简介

管华诗,男,1939年8月28日出生,山东省夏津人。1964年毕业于山东海洋学院(现中国海洋大学)水产品加工专业,大学本科学历。现任山东省科协主席、中国科协常委、中国工程院院士、十届全国人大代表,中国海洋大学校长;兼任国家重点基础研究发展规划第三届专家顾问委员组成元,国务院学位委员会第五届学科评议组成员。管华诗院士长期从事海洋生物资源的综合开发利用及海洋药物与食品工程教学和科研工作,特别是对海洋多糖化学及其开发研究有较长时间的积累,并有较深的造诣;建立了海洋药物研究开发、工程化、产业化的完整配套技术体系;研制发明了具有国际先进水平的治疗缺血性心脑血管疾病的我国第一个海洋现代新药“藻酸双脂钠(PSS)”,之后,又相继成功研制了降脂新药“甘糖酯”、保肝抗癌的“海力特”、降糖新药“降糖宁”及系列海洋生物的制品;获授权国内外发明专利11项,申请国家发明专利27项。他的研究成果基本实现了产业化,取得了显著的经济和社会效益,从而推动了海洋药物的研究与生长,为我国海洋制药业雏形的形成做出了基础性贡献。目前,主持研制的两个国家一类新药已进入了Ⅱ期临床研究。管华诗院士曾获得全国科技大会奖、国家科技进步三等奖、山东山东省科技进步一等奖、美国世界成就奖等10余项奖励。

  • [英文]    Structural studies on K-carrageenan derived oligosaccharides
  • Author(s):Guangli Yu,a Huashi Guan,a Alexandra S. Ioanoviciu,b Sulthan A. Sikkander,b Charuwan Thanawiroon,b Joanne K. Tobacman,c Toshihiko Toida,d Robert J. Linhardtb,*
  • Affiliation:a Marine Drug and Food Institute, Ocean University of Qingdao, Qingdao 266003, People's Republic of China b Department of Medicinal and Natural Products Chemistry, Chemistry, and Chemical and Biochemical Engineering, College of Pharmacy, University of Iowa, Iowa City, IA 52242, USA c Department of Internal Medicine, University of Iowa Health Care, Iowa City, IA 52242, USA d Department of Bioanalytical Chemistry, Graduate School of Pharmaceutical Sciences, Chiba Uni ersity, Chiba 263-8522, Japan
  • Source:Carbohydrate Research 337(2002)433-440
  • [英文]    Analysis of oligomannuronic acids and oligoguluronic acids by high-performance anion-exchange chromatography and electrospray ionization mass spectrometry
  • Author(s):Yan Liuaa*, Xiao-Lu Jianga, He Cuib, Hua-Shi Guana
  • Affiliation:a Food Science and Technology, Fishery College, Ocean University of Qingdao, Qingdao 266003, China b Laboratory of Food Inspection, Shandong Entry-Exit Inspection and Quarantine Bureau, Qingdao 266002, China
  • Source:Journal of Chromatography A, 884(2000)105-111
  • [英文]    The potential molecular targets of marine sulfated polymannuroguluronate interfering with HIV-1 entry Interaction between SPMG and HIV-1 rgp120 and CD4 molecule
  • Author(s):Geng Meiyu, Li Fuchuan, Xin Xianliang, Li Jing, Yan Zuowei, Guan Huashi
  • Affiliation:Department of Marine Pharmacology, Marine Drug and Food Institute, Ocean University of China, 5 Yushan Road, Qingdao 266003, PR China
  • Source:Antiviral Research 59(2003)127-135
  • [英文]    Synthesis and magnetic studies of oxalato-bridged copper (II)-chromium (III)-copper (II) and copper (II)-iron (III)-copper (II) heterotrinuclear complexes
  • Author(s):Yan-Tuan Lia,*, Cui-Wei Yanb, Hua-Shi Guana
  • Affiliation:a Marine Drug and Food Institute, Ocean University of China, 5 Yushan Road, Qingdao, Shandong 266003, PR China b College of Marine Life Sciences, Ocean University of China, Qingdao 266003, PR China
  • Source:Polyhedron 22(2003)3223-3230
  • [英文]    Metal-N-saccharide chemistry: synthesis and structure determination of two Cu (II) complexes containing glycosylamines
  • Author(s):Wei Zhang,a Tao Jiang,a,* Sumei Ren,a Zhongwei Zhang,a Huashi Guana and Jingsheng Yub
  • Affiliation:a Marine Drug and Food Institute, Ocean University of China, Qingdao 266003, China b The Key Laboratory for Supramolecular Structure and Materials of Ministry of Education, Jilin University, Changchun 130023, China
  • Source:Carbohydrate Research 339(2004)2139-2143

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