The Application and Assessment of Ketamine–Xylidinothiazoline Combinations for Anaesthesia in Rhesus Monkey
首发时间:2008-01-07
Abstract:To access the different effects of between ketamine and ketamine-Xylidinothiazoline in anesthesia of rhesus monkeys. 20 Rhesus Macaque were anesthesia with tow kinds methods in this experiment. The anesthesia effects were evaluated during anesthesia. At the same time the cardiovascular parameters, and respiration parameters were monitored with Datex circulation, respiration monitor and multi-functional physiologic graphed SJ-42 continuously and dynamically. The results showed that the effects of anesthesia was good, it reach the surgical anesthetic depth. The relation between analgesia, sedation and muscle relaxation were balanced. The induction time were 5.0±1.6min and the anesthesia maintained 55.3±6.6min in all. Furthermore the compound anesthetic has little effects on the physiology function of Rhesus Macaque and heart rate, blood pressure, blood oxygen saturation, body temperature, respiratory rate maintain in normal physiological range during anesthesia. It was evident that the compound anesthetic can meet the clinical needs.
keywords: Ketamine Xylidinothiazoline Rhesus Monkey Anaesthesia
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氯胺酮与氯胺酮-静松灵对猕猴麻醉效果的应用与评价
摘要:为评价氯胺酮,氯胺酮-静松灵对猴的不同麻醉效果,本实验二种麻醉方法对20只猕猴进行临床麻醉。麻醉期间观察麻醉效果并利用CardiocapTMⅡCH-RS—循环呼吸监护仪、 SJ—42多导生理记录仪对动物呼吸系统及循环系统的生理指标进行监测。结果表明:该氯胺酮—静松灵复合方法对猕猴的麻醉效果确实并达到外科麻醉深度;镇痛、镇静、肌松效果均衡;麻醉诱导时间为5.0±1.6min,麻醉维持时间为55.3±6.6min;猕猴在麻醉期间心率、血压、血氧饱和度、体温、呼吸率等指标均维持在正常生理范围之内。该复方麻醉剂可以满足猕猴临床麻醉的需要。
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No.1784017894611996****
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