THE STUDY ON THE SPECTROSCOPIC PROPERTIES OF THE MODIFIED PHOTOSENSITIZER HYPROCRELLIN A

• 1、Key Laboratory of Polarized Laser and Information Technology, Laser Institute of QuFu Normal University , 273165 , Shandong , PRCCollege of Physics and Engineering ， QuFu Normal University 273165 Shandong , PRC
• 2、College of Physics and Engineering, QuFu Normal University
• 3、Key Laboratory of Polarized Laser and Information Technology, Laser Institute of QuFu Normal University
• 4、Key Laboratory of Polarized Laser and Information Technology, Laser Institute of QuFu Normal University
• 5、Institutes of Modern Optics, Nankai University, Tianjin

Abstract：At present, functional organic molecule is a study focus in exploitation of new type photoelectron material and photosensitizer of photodynamic therapy (PDT)，So,It is very important to study and exploit the new-type photosensitizer.In order to modify hypocrellin A (HA) while maintaining its excellent sensitivity to singlet oxygen , work has been done to recognise its spectroscopy and electronic excited state properties .We study systemically the absorption and fluorescence spectrum of HA in different acidity and basicity, and obtain some new and basic evidences to support that the absorption band I results fromπ→π* transition; the long wavelength absorption band II and III results from L→απtransition; and the fluorescence emission results from the transition of S1 (L,aП) →S0 with the similar vibronic featrues to absorption band. Furthermore ,We study spectrums of HA dispersed in sieves (MCM-41) in details, A new emission band of HA in sieves is observed at long wavelength side under strong pulse laser excitation., Which is corresponding to that in the solution of HA under the same excitation . We believe it results from the fluorescence of ESIPT produced by double -photon absorption.

Keywords： Hypocrellin A Photodynamic therapy(PDT) Excited state intramolecule proton transfer(ESIPT) sieves