1010例唇腭裂患者的临床资料分析
首发时间:2009-08-10
摘要:目的 了解先天性唇腭裂的患病状况与特点,分析与唇腭裂发生有关的影响因素,为唇腭裂病因探讨及预防提供依据。方法 对2000年1月-2009年3月住院的1010例先天性唇腭裂患者进行回顾性统计分析。结果 本组病例中,单纯唇裂为222例(21.98%),唇裂伴腭裂为620例(61.39%),单纯腭裂为168例(16.63%);总体男性多于女性(1.89:1),但在不完全腭裂中,女性多于男性(1:0.77);单侧唇裂伴或不伴腭裂及完全腭裂中,左侧多于右侧(1.71:1);有遗传史的病例数为64例,占总例数的6.34%;唇腭裂患者母亲妊娠前3个月接触风险因素者有356例(35.25%)。结论 唇腭裂的病因是复杂的,婚前遗传病的检测和孕期保护是目前降低唇腭裂发生率的重要措施。
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Statistical analysis of 1010 patients with cleft lip and palate
Abstract:Objective In order to know the clinical and deformity condition in patients with cleft lip and palate, analyze certain specific related factors with cleft lip and palate, as well as furnish evidence for etiology and prevention to cleft lip and palate. Methods 1010 patients were surveyed and their clinic data were analyzed statistically. Results There were cleft lip 222 cases (21.98%), cleft lip with cleft palate 620 cases (61.39%), and cleft palate 168 cases (16.38%). Males were more than females (1.89:1) in all cases, but in uncompleted cleft palate, females were more than males (1:0.77). The left side is more than the right side (1.71:1) in cases of the unilateral cleft lip with or without palate and the completed palate. 64 cases (6.34%) had definitive genetic factor. Mother underwent danger factors in the first three months of pregnancy: 356 cases (35.25%) were found in all cases. Conclusions The cause of the cleft lip and palate is complicated. At present, detection of genetic disease before marriage and pregnancy protection is an important measure to reduce the incidence of cleft lip and palate.
Keywords: Cleft lip Cleft palate Etiology
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