芒果苷药代动力学及体内代谢产物研究进展
首发时间:2012-04-09
摘要:芒果苷是高等植物中广泛存在的一种多酚,具有多种生物学功能。但目前人们对芒果苷在体内的代谢研究仅限于动物实验研究,其作用是否如学者推测来自于其代谢产物仍不得而知。本文正是从该点出发,对芒果苷在体内的药代动力学及其代谢产物作一综述,期望为芒果苷的应用及芒果苷代谢产物的研究提供思路。
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Pharmacokinetics and metabolites of mangiferin in vivo
Abstract:Mangiferin, a polyphenol widely existing in higher plant, was reported to have various bioactivities. Until now, the metabolic fate of mangiferin in vivo was mainly based on animal experiments. Whether bioantivities of mangiferin came from its metabolites or not, as some researchers speculated, was not established yet. Given the status, the pharmacokinetics of mangiferin and the metabolites of mangifeirn in vivo were reviewed here and the present paper was expected to give clues for future studies on utility of mangiferin and the metabolites of mangiferin.
Keywords: Mangiferin pharmacokinetics metabolites in vivo
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