滋阴益气活血解毒法治疗2型糖尿病合并脂肪肝临床观察
首发时间:2013-01-21
摘要: 目的:探讨滋阴益气活血解毒法对2型糖尿病(T2DM)合并脂肪肝(NAFLD)患者空腹血糖、血脂、肝功能、肝脏影像学的影响。方法:将符合入选标准的60例患者随机分为对照组和治疗组,各为30例,均进行糖尿病常规治疗-饮食体质量控制、加强运动并使用口服降糖药物调节血糖。对照组服用肝旨清胶囊,治疗组服用肝旨清胶囊加用滋阴益气活血解毒组方中药治疗。两组疗程均为5个月,评定治疗后的临床疗效。结果:两组病例治疗前各项检查指标比较无统计学意义(P> 0.0 5);经治疗后,对照组和治疗组空腹血糖、餐后2h血糖、血脂、肝功能和脂肪肝等级与治疗前比较,差异具有统计学意义( P< 0.0 5或0.0 1),除空腹血糖外,治疗组各项检查指标优于对照组,差异具有统计学意义( P< 0.0 5或0.0 1);治疗组总体疗效优于对照组,,差异具有统计学意义( P< 0.0 1 )。结论:滋阴益气活血解毒法对2型糖尿病合并脂肪肝患者空腹血糖、血脂、肝功能均有改善作用。
关键词: 2型糖尿病合并脂肪肝 肝功能 滋阴益气活血解毒法
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Study on clinical efficacy of the mothod of Ziyin Yiqi Huoxue Jiedu imposed on the type 2 mellitus with non-alcoholic fatty liver
Abstract:Objective: To observe the clinical efficacy of the mothod of Ziyin Yiqi Huoxue Jiedu imposed on the type 2 mellitus with non-alcoholic fatty liver. Method: Te selected 60 patients with type 2 diabetes mellitus with non-alcoholic fatty liver which were diagnosed with de?ciency of both yin and qi, turbid phlegm blood stasis by TCM. These patients were divided into control and therapy groups randomly. They all performed basic treatment, like oral antidiabetic drug and ,Liver purpose Qing Capsule,diet control as well as more exercise to regulate the blood glucose level, while the patients of therapy group, in addition to the above treatment, were given the Chinese medicine of Ziyin Yiqi Huoxue Jiedu . The treatment period was 5 months. Liver ultrasound examination and biochemical tests (the fasting blood glucose , 2 hour postprandial blood glucose,including blood lipid, liver function) as well as the total effect were carried out for those 60 patients before and after the treatment. Result: There was no signi?cant difference between the fatty liver degree and biochemical tests of two groups before treatment(P> 0.0 5).After 5 months, the blood glucose, 2 hour postprandial fasting blood glucose,the blood lipid, liver function and the fatty liver degree of the two groups were all improved to different degrees( P< 0.0 5,0.0 1), and those of the therapy group except thefasting blood glucose improved more signi?cantly( P< 0.0 5,0.0 1). There was signi?cant difference between tthe total effect of two groups after treatment( P< 0.0 1 ). Conclusion: The mothod of Ziyin Yiqi Huoxue Jiedu had a favourable curative effect on the type 2 diabetes mellitus with non-alcoholic fatty liver.
Keywords: the type 2 mellitus with non-alcoholic fatty liver liver function Ziyin Yiqi Huoxue Jiedu
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滋阴益气活血解毒法治疗2型糖尿病合并脂肪肝临床观察
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