三环咔唑生物碱基本骨架的一种简洁合成方法
首发时间:2013-11-20
摘要:以3位溴代的吲哚化合物和环丁烯二酮类化合物为起始原料,通过它们之间的加成和扩环重排过程,实现了三环咔唑类生物碱基本骨架的有效构建,从而为具有重要生物活性的多种三环咔唑类生物碱的合成研究发展出一种简洁的合成方法。
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A Concise Synthetic Method to Basic Skeleton of Tricyclic Carbazole Alkaloid
Abstract:Starting from 3-bromide indole and cyclobutenedione type compound, the basic skeleton of tricyclic carbazole alkaloid has been efficiently constructed through their addition and ring expansion process. Therefore, a concise synthetic method has been developed for the synthetic studies of various tricyclic carbazole alkaloids with important bioactivity.
Keywords: Organic Synthesis Basic Skeleton Carbazole Alkaloid Synthetic Method
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