组蛋白修饰与DNA及microRNA甲基化在胃癌中的研究进展
首发时间:2014-01-09
摘要:表遗传学修饰在胃癌的发生、发展中起重要作用,组蛋白修饰与DNA甲基化及microRNA甲基化作为表遗传学的重要组成部分已成为研究的热点.大量研究发现蛋白修饰与DNA甲基化及microRNA甲基化在胃癌中分别发生了不同程度的改变, 这种变化具有重要的临床价值,可能成为判断肿瘤生物学特性及临床预后的重要指标之一。本文就与胃癌相关的组蛋白修饰与DNA甲基化及microRNA甲基化研究进展作一综述.?????
关键词: 胃癌 DNA甲基化 组蛋白修饰 microRNA甲基化
For information in English, please click here
Advances in Study on Histone Modification and Methylation of DNA and microRNA in Gastric Cancer
Abstract: Histone modification and methylation of DNA and microRNA, as important components of epigenetics that plays vital role in the development and progress of gastric cancer, has become a research hotspot. Accumulating studies have demonstrated that changes in Histone modification and methylation of DNA and microRNA occurred in gastric cancer, having significant value in clinical practice and May become the judge one of the important indexes of tumor biological characteristics and clinical outcome.This article reviewed the recent advances in study on Histone modification and methylation of DNA and microRNA in gastric cancer.?????
Keywords: gastric cancer Histone Modification DNA Methylation microRNA Methylation
论文图表:
引用
No.****
同行评议
共计0人参与
勘误表
组蛋白修饰与DNA及microRNA甲基化在胃癌中的研究进展
评论
全部评论0/1000