The employment of Porous Portion to Simulate Pulmonary Vascular Resistance in the Computational Fluid Dynamic Models of Total Cavo-pulmonary Connection

• 1、Department of Cardio-thoracic Surgery,Shanghai Children's Medical Center,School of Medicine,Shanghai JiaoTong University,Shanghai 200127
• 2、School of Medicine,Shanghai JiaoTong University,Shanghai 200025

Abstract：In this study, we performed computational fluid dynamic (CFD) simulations in a patient-specific three-dimensional extracardiac conduit total cavopulmonary connection(TCPC). The pulmonary vascular resistance(PVR) was incorporated in the CFD model by connecting porous portions in the left and right pulmonary arteries. The pressure in the common atrium was set as boundary conditions at the outlets of the pulmonary arteries. The flow rate in the innominate veins and the inferior vena cava (IVC) was set as inflow boundary conditions. Furthermore, the inflow rate of IVC was increased to 2 and 3 times of that measured to perform another two simulations and the resistance provided by the porous portions was compared among these three conditions. We found out that the PVR set as porous portion in the CFD models remains relatively steady despite the change of the inflow rate. We concluded that, in the CFD simulations for the TCPC, porous portion could be used to represent PVR steadily. The PVR and pressure in the common atrium could be acquired directly by clinical examination. The employment of porous portion together with pressure in the common atrium in the CFD model could facilitate and accurate the set of outlet boundary conditions especially for those actual pulmonary flow splits was unpredictable such as virtual operative designs related CFD simulations.

Keywords： porous portion pulmonary vascular resistence total cavo-pulmonary connection computational fluid dynamics