变温拉曼光谱和DSC探讨人参皂苷Rb1分子与DPPC双层膜的作用
首发时间:2014-05-20
摘要:采用变温拉曼光谱和差示扫描量热技术(DSC)探讨了人参皂苷Rb1与DPPC双层膜的作用。结果表明,随着温度的增加,含有一定浓度Rb1的DPPC磷脂极性头部旁氏构象没有发生变化,脂酰链的无序性构象增多,脂双层的流动性增加。DSC实验进一步验证了变温拉曼实验结果,说明Rb1对DPPC双层膜的影响较大。
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Study on the Effect of Ginsenoside Rb1 on DPPC Bilayers by using Thermo-Raman Spectrum and DSC
Abstract:In this paper, the influence of ginsenoside Rb1 on DPPC membrane bilayers was investigated by thermo - Raman and differential thermal scanning technology ( DSC ). Raman results showed that ginsenoside Rb1 molecule of certain concentration has not changed the gauche conformation of the polar head backbone group in DPPC bilayers, the order of the internal molecular chain and the lateral chain-chain packing have been decreased as the temperature increased, and the fluidity of bilayers increased. The DSC showed further results of the thermo - Raman experiments, which indicated that the strong effects of ginsenoside Rb1 on DPPC.
Keywords: thermo - Raman DSC ginsenoside Rb1 DPPC bilayers
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No.4596629975865139****
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变温拉曼光谱和DSC探讨人参皂苷Rb1分子与DPPC双层膜的作用
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