The Febrication of Flexible Glucose electrocheimstry Biosensors

• 1、College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005

Abstract：The continuous measurement of blood glucose is an important issue in the treatment of diabetes. Due to its rigid structure and lack of biocompatibility, the majority glucosemeter can only be used for measuring in vitro. This research embarks from the construction of flexible glucose sensor and multiwalled carbon nanotubes (MWCNTs) and chitosan (CTS) compounds were used as supporting material for the immobilization of enzymes. Silicone rubber which is flexible and possesses good biocompatibility was used as substrate in fabricating the electrode. Glucose dehydrogenase (GDH) was employed as biocatalyst to catalyze glucose and nicotinamide adenine dinucleotide （NAD）was worked as coenzyme. The electrochemical properties and the ability to oxidase glucose of the bioelectrode were investigated. The results showed that the bioelectrode showed good linear response to the glucose whose concentration was between 6 mM and 20 mM which showed the potential application for blood glucose test.

Keywords： Electrochemistry glucose sensor silicone rubber flexible carbon nanotube