健脾益气摄血方对ITP模型小鼠外周血象的影响
首发时间:2015-06-18
摘要:目的 研究健脾益气摄血治则对ITP小鼠外周血象的影响。方法 制备豚鼠抗小鼠血小板血清(APS),注射于BALB/c小鼠体内造成ITP小鼠模型,模型稳定后给予强的松和健脾益气摄血颗粒干预,检测小鼠外周血象的变化情况。结果 注射APS造模后,小鼠外周血血小板计数减少,白细胞计数升高,血红蛋白含量降低,血小板分布宽度基本无影响;给药干预后,血小板计数回升,白细胞计数降低,但与药物作用不相关,血红蛋白含量回升,血小板分布宽度无影响。结论 健脾益气摄血治则能够有效提升ITP小鼠血小板数量及血红蛋白含量。
For information in English, please click here
Effect of prescription JIANPIYIQISHEXUE on the peripheral hemogram of ITP mice model?
Abstract:Objectives: To investigate the effect of prescription JIANPIYIQISHEXUE on the peripheral hemogram of ITP mice model. Methods: The guinea pig anti-platelet serum (APS) in mice was prepared, and injected to BALB/c mice to establish ITP mice model. Prednisone and prescription JIANPIYIQISHEXUE (granules) were given to the ITP mice, and the changes of peripheral hemogram were detected. Results: After injection of APS, the PLT and Hgb reduced, WBC raised, no change in PDW. After given the drugs, PLT and Hgb recovered to the normal level, WBC reduced but not related to the drugs, and no change in PDW. Conclusions: Prescription JIANPIYIQISHEXUE effectively enhanced the content of PLT and Hgb in ITP mice.
Keywords: JIANPIYIQISHEXUE ITPmodel Peripheral hemogram
论文图表:
引用
No.4645685405731432****
同行评议
共计0人参与
勘误表
健脾益气摄血方对ITP模型小鼠外周血象的影响
评论
全部评论0/1000