胰岛内分泌β细胞上的离子通道及其生理功能
首发时间:2015-11-24
摘要:胰岛素由胰腺β细胞通过胞吐的方式分泌入血。与其它许多内分泌细胞类似,胰腺β细胞上的电信号活动是调节胰岛素分泌的重要机制之一。本文综述了胰腺β细胞上参与胰岛素分泌的各离子通道的结构,分型及主要生理功能。
关键词: 内分泌 胰岛β细胞 ATP-敏感性K+通道 电压依赖性K+通道 电压依赖性Ca2+通道
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Structure, classification and physiological properties of ion channels in pancreatic β-cells
Abstract:Insulin is secreted from pancreatic β-cells by exocytosis into the blood stream. As many other endocrine cells, the electrical activity of the pancreatic β-cells is one of the important mechanisms for regulating insulin secretion. This paper reviews the structure, classification and the physiological properties of the ion channels in pancreatic β-cells.
Keywords: Endocrinology;Pancreatic islet β-cells; KATP;KV;VDCC
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No.4662610103313214****
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