蛋白质-RNA模板数据库的构建
首发时间:2015-12-17
摘要:数据库在研究蛋白质-RNA的相互作用中是十分重要的,因此在本文中我们构建了一个数据库。从PDB数据库下载到所有的蛋白质-RNA的复合物坐标文件,之后选择长度、分辨率、界面残基的个数等条件对PDB的复合结构进行筛选,聚类构成模板库,构建出一个包含633个界面,208个复合物的模板库,以此作为下一步研究的数据集基础。。
关键词: 生物物理 蛋白质-RNA 模板 二元界面 RNA二级结构
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The construction of protein-RNA template database
Abstract:Database plays a important role in the research of protein RNA interaction, so we constructure a database in this research. We downloaded all protein-RNA complex coordinate file from the PDB database, and then different conditions were selected to filter the PDB file, the RNA chains were clustered by blastcluster to constuctute a non-redunent data. Finally we get a database contained 633 interfaces and 208 complexes, this database will be used in further research.?????
Keywords: biophysics protein-RNA template binary interface RNA secondary structure?????
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