过敏性紫癜相关基因多态性的研究进展
首发时间:2016-06-03
摘要:近年来众多研究发现,某些基因及其多态性与过敏性紫癜的发病机制、易感性、病理进展及预后相关,如人类白细胞抗原基因、肾素-血管紧张素系统基因、细胞因子基因等。因此对过敏性紫癜相关基因的研究现状进行综合分析将为今后从基因水平认识过敏性紫癜疾病的本质、研究新的治疗方案提供重要理论依据。
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Research Advances of Henoch-Sch?nlein Purpura-related Genes Polymorphisms
Abstract:Recently years, numerous studies have found that certain genes and their polymorphism are closely associated with the pathogenesis, susceptibility, progression and prognosis of HSP, for example human leukocyte antigen genes, renin-angiotensin system genes, cytokine genes, e.g. Therefore, comprehensive analysis of the recent advances of HSP-related genes will provide important theoretical foundation for understanding the nature of HSP from gene level and developing new treatment in future.
Keywords: Pediatric;Henoch-Sch?nlein purpura;Genes;Polymorphisms
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