一种抗血氧波动干扰的无创心输出量检测方法
首发时间:2016-06-21
摘要:心输出量是评估心脏健康状况的重要指标,在临床的急危重症病情评估与手术监测中具有重要参考价值。当前临床上无创获取心输出量的方法是脉搏色素分光光度法,该方法以血氧饱和度为100%作为基础,通过测量吲哚菁绿色素浓度来间接计算出心输出量,这将导致心输出量的计算值存在一定误差。针对该问题,本文提出了一种抗血氧波动干扰的无创心输出量检测方法,以朗伯-比尔定律为理论基础,实现了对脉搏色素分光光度法测量的吲哚菁绿色素浓度的修正。在人体注入吲哚菁绿后,在人体指端采集660nm,805nm和940nm的三波长透射信号,将采集到的数据上传至上位机,通过计算得到吲哚氰绿色素的浓度曲线,从而计算出心输出量。将本文所提方法与脉搏色素分光光度法的测量结果分别跟目前测量心输出量最准确的热稀释法的测量结果相比较,测量误差得到了明显的改善。实验结果表明,该方法提高了心输出量测量的精确度,为临床提供了一种更加准确的心输出量检测方法。
关键词: 光电子学与激光技术 吲哚菁绿 脉搏波 心输出量 脉搏色素分光光度法
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A Measurement Method for the Cardiac Output Anti Oxygen Fluctuations
Abstract:Cardiac output is a important index in evaluating cardiac health, has important reference value in the critical condition assessment and surgery monitoring. The current clinical noninvasive method for cardiac output is pulse dye spectrophotometry, the method takes the blood oxygen saturation is 100% as the foundation, by measuring the indocyanine green pigment concentration indirectly calculated cardiac output, this will lead to the calculated value of cardiac output there is a certain error. Aimed at this problem, this paper puts forward a kind of anti oxygen noninvasive cardiac output fluctuation interference detection method, based on the theory of lambert - beer's law, realized with pigment of spectrophotometry measuring pulse indocyanine green pigment concentration of correction. After injection of indocyanine green in the human body, collected 660 nm, 805 nm and 940 nm wavelength transmission signal in the human fingers, then upload the data to the computer, indole cyanogen green pigment concentration curve and cardiac output is obtained by calculation. In this paper, the proposed method and pulse dye spectrophotometry measuring results, respectively, with the most accurate measurement of cardiac output in comparison with the measured results of thermal dilution method, measurement error is obviously improved. The experimental results show that the method improve the accuracy of measurement of cardiac output, for clinical provides a more accurate detection method in cardiac output.
Keywords: Optoelectronics and laser technology Indocyanine green(ICG);Pulse wave;Cardiac output;Pulse dye spectrophotometry
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