内毒素在肥胖相关慢性炎症中作用的研究进展
首发时间:2016-11-24
摘要:肥胖及其相关代谢异常疾病目前成为严重的公共卫生问题。慢性炎症反应与肥胖、胰岛素抵抗等疾病密切相关,这种炎症反应可由脂肪组织分泌的因子诱发,此外肠道菌群相关的内毒素水平异常增高也引起慢性炎症反应,动物试验中有较多相关报道,却缺乏足够的相关人体试验。本文介绍了LPS在慢性炎症反应中作用的研究进展,为肥胖的治疗方向提供思路。
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The progress of LPS effection on obesity related chronic inflammation
Abstract:Obesity and obesity related metablic disease are becoming serious public problem. Chronic inflammation is related with several disease including obesity and insulin resistant.It was trigered by factors secreting by fat tissue.Furthermore,it also can be induced by elevated serum LPS concentration.There were many reports from animal experiments but abscent of human evidence.The article introduce the progress of LPS on chronic inflammation in order to explore the possible theraputic methods.
Keywords: pediatrics LPS obesity chronic inflammation
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