砷的生殖毒性研究
首发时间:2017-05-11
摘要:砷导致的生殖系统毒性已引起越来越多的关注,流砷的生殖毒性研究行病学资料和动物实验均证实了砷对暴露者的生殖毒性作用。本文从生殖细胞、胚胎及激素水平的变化等方面分析总结近几年砷导致的人类及动物生殖毒性研究,包括精子数量及活力下降、精子畸形增加、睾丸组织结构受损、睾酮及黄体生成素等激素水平改变,母亲孕期砷暴露造成的流产、畸形、死胎及低出生体重儿等生殖毒性作用。
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Study on Reproductive Toxicity of Arsenic
Abstract:In this paper, arsenic-induced reproductive system toxicity has attracted more and more attention, the study of arsenic reproductive toxicity research and animal experiments have confirmed the arsenic exposure to the reproductive toxicity of the role. This paper summarizes the arsenic-induced human and animal reproductive toxicity studies in recent years from the aspects of changes in germ cells, embryos and hormones, including decreased sperm count and viability, increased sperm deformity, impaired testicular tissue structure, testosterone and luteinizing hormone Such as changes in hormone levels, maternal arsenic exposure caused by miscarriage, deformity, stillbirth and low birth weight and other reproductive effects of children.
Keywords: Arsenic germ cell toxicity embryo toxicity and hormone levels
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