紫杉烷类抗肿瘤药研究进展
首发时间:2017-06-09
摘要:紫杉烷类药物如紫杉醇与多西紫杉醇为近二十年出现的治疗恶性肿瘤的强效药物,它们具有广谱的抗肿瘤药物活性。目前紫杉烷类药物的研究应用主要集中在配合其他药物的联合疗法上,本文综述了紫杉烷类药物的体内过程、药理作用机制、临床应用等等,所有这些研究均有助于对紫杉烷药物的用药剂量与用药方法提供参考,将有助于提高患者的顺应性及临床对于实体瘤的疗效。
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Progress in the Study of Taxanes against Tumor
Abstract:For the past two decades, Taxanes such as paclitaxel and docetaxel has been seen as a powerful drug for the treatment of malignant tumors, they have a broad spectrum of antineoplastic activity. Currently application of taxanes focus on combination therapy with other drugs, this paper reviews the process of taxanes in vivo, pharmacological mechanism of action, clinical application and so on,all these studies are useful to provide guidance on dosage and method of administration for taxanes,this will improve patient compliance and clinical efficacy for solid tumors.
Keywords: taxane;paclitaxel;docetaxel;antitumor;process in vivo
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No.4736835112272714****
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