H-型血管及其在骨关节炎方面的研究进展
首发时间:2017-08-16
摘要:H-型血管是一种新近发现的特殊的血管亚型,主要分布在长骨干骺端,能加速骨的形成,促进骨量增多。H-型血管随着年龄的增长逐渐减少,同时伴随着干骺端骨形成的减少,证实其与新生骨有着密切的关系。骨关节炎的重要病理改变之一是软骨下骨的骨量增多及重塑。近来研究发现,在骨关节炎发病进程中软骨下骨的H-型血管生成增多,可能加速软骨下骨的骨形成及重塑,从而促进骨关节炎。本文将结合国内外对H-型血管的最新研究成果,重点讨论H-型血管的功能以及在骨关节炎方面的研究进展。
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Research advance of H-type vessel and its role in osteoarthritis
Abstract:H-type vessel is a newly discovered special subtype of vessels, mainly distributed in the metaphysis of the long diaphysis. It accelerates bone formation and increases bone mass. H-type vessel gradually decreased with age, accompanied by the reduction of metaphyseal bone formation, which confirmed that it was closely related to the formation of new bone. Subchondral bone mass increasing and remodeling is an important pathological change of osteoarthritis. In recent years, increasing H-type vessels in subchondral bone of osteoarthritis have been found, which may accelerate the subchondral bone formation and remodeling and promote the progress of osteoarthritis. This article will combinate with the latest research results at home and abroad of H-type vessel, and discuss mainly about the functions of H-type vessel and its research progress in osteoarthritis.?
Keywords: Osteoarthritis H-type vessel mechanical stress subchondral bone
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