减轻体重对PCOS患者血清脂联素水平的影响
首发时间:2018-02-28
摘要:目的:探讨减轻体重对多囊卵巢综合征(PCOS)患者血清脂联素水平的影响。方法:纳入PCOS患者150例,检测所有患者体重改变前后的血清脂联素水平,分析患者血清脂联素水平变化与体重改变的关系。结果:按照体重指数将患者分为3组,结果显示脂联素水平在BMI18.7 kg/m2-19.9 kg/m2组和BMI24.0 kg/m2-25.8kg/m2组间有统计学差异[(9.7?2.8) ?g/L vs (7.3?2.7) ?g/L , P<0.05)]; 按照患者的减重幅度将以上患者分为3组:减重-0.8-1.5kg为A组,减重1.5-3.0kg为B组,减重3.0-4.7kg为C组,B组和C组患者减重前后的血清脂联素水平有统计学差异。结论:PCOS患者的血清脂联素水平与体重指数呈负相关,减轻体重可以增加患者的脂联素水平。
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Effect of weight loss on serum adiponectin concentration in patients with Polycystic Ovary Syndrome
Abstract:Object: To study the effect of weight loss on serum adiponectin concentration in patients with Polycystic Ovary Syndrome. Methods: the study involved 150 patients with PCOS, who was divided into 3 groups according to their body mass indecx(BMI). All patients were detected serum adiponectin levels before and after their weight loss and comparison of serum adiponectin level was made to evaluate the change of serum adiponectin concentration associated with weight loss. ResultsThe effect of weight loss on serum adiponectin concentration in patients with Polycystic Ovary Syndrome : Serum adiponectin level was decreased with body mass index increasing in PCOS patients. Serum adiponectin was increased after weight loss. In the patients who didn\'t lose weigh(weight loss -0.8-1.5kg) there was no change of serum adiponectin levels. Conclusion: Serum adiponectin levels was negatively correlated with body mass index in PCOS patient and weight loss can increase serum adiponectin concentration in PCOS patients.
Keywords: Polycystic ovary Syndrome adiponectin body mass index
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