关于发热模型的述评
首发时间:2018-03-02
摘要: 发热是由于致热原的作用使体温调定点上移而引起的调节性体温升高。发热模型的建立为我们进一步在实验中研究发热症状及机理奠定了基础。发热有不同类型,因此在实验中根据所研究的发热类型选择合适的发热模型就至关重要。本文对近年来发热动物模型及造模药物作一综述,归纳了不同动物模型及造模药物的特点,并对目前发热模型建立的一些问题提出了相应对策。
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A Review of Fever Animal Models
Abstract:Fever is due to the role of the heat source so that the body temperature set point adjustment caused by the regulation of body temperature.The establishment of fever model lays the foundation for further study on fever symptoms and mechanism in the experiment. There are different types of fever, so it is important to choose the right fever model based on the type of fever studied. This article summarizes the experience of both animal models and model drugs in the fever model in recent years, summarizes the characteristics of different animal models and modeling drugs, and puts forward some countermeasures to some problems of the current fever model.
Keywords: Fever Animal model;drugs
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