Photothermal effects of Au-Ag nanocups

• 1、College of Chemistry and Chemical Engineering,Hunan University,Changsha 410082

Abstract：Au nanomaterials have a wide range of applications in the fields of analytic detection, catalysis, nano-devices and medical care because of their unique optical and catalytic properties.In particular, Au nanomaterials were expected to be an effective candidate for cancer therapy because of the heat effect induced by its LSPR property. Generally, LSPR peak of Au nanospheres is around 520 nm, which would be strongly absorbed and scattered by biological tissues, severely limiting their application in vivo. In order to improve the photothermal conversion efficiency of Au nanomaterials Au-Ag nanocups were prepared by oriented etching of Ag cubes at water/air interface. In vitro photothermal experiment, when AuAg "nanocups" solution was irradiated with 808 nm laser, the temperature can reach 49.7 C and no obvious change in the photothermal effects was observed after four cycles of heating and cooling processes at a higher power density , exhibiting excellent chemical stability. At lower concentrations, when irradiated with 808 nm, the survival rate of HeLa cells is higher than 50%,showing satisfactory performance for killing tumor cell.

Keywords： Physical chemistry Au-Ag nanpcups Photothermal effects