Clinical analysis of 120 cases of multiple primary cancer

• 1、Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine,beijing 100700

Abstract：To explore the etiology,clinical features, treatment and prognosis of multiple primary cancer.Methods:The medical records of 120 patients with multiple primary cancers from the Department of Hematology,Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine from January 1,2008 to January 1,2018 were collected and analyzed retrospectively.Results:①Among 120 patients with multiple primary cancer,62 were males and 58 were females;②The age of onset is 26-89 years old,with a median age of 58 years;③There were 116 cases of dClinical analysis of 120 cases of multiple primary cancerouble primary malignant tumors,2 cases of three primary malignant tumors,1 case of four primary malignant tumors and 1 case of five primary malignant tumors;④There were 25 cases of simultaneous multiple carcinoma,accounting for 20.8%,and 95 cases of metachronous multiple cancer,accounting for 79.2%.The interval between onset was 6 months to 444 months,and the median interval was 32 months;⑤The first malignant tumor is the most common digestive system, followed by the reproductive system,respiratory system and urinary system.The second primary malignant tumor is the most common blood system,followed by the respiratory system,digestive system and reproductive system;⑥The 3-year and 5-year survival rates were 48.3% and 37.5%,respectively;⑦Thirty-three of the 120 patients were solid tumors with hematologic malignant tumors.Conclusion:Through analysis,we can improve the understanding of multiple primary cancer,guide the early clinical detection and early diagnosis and early treatment,so as to prolong the patient\'s life and improve the prognosis. With comprehensive treatment,radical surgical treatment is the first choice.

Keywords： Multiple primary cancers；Diagnosis；Treatment；The prognosis