牙周炎与非酒精性脂肪肝的关系分析
首发时间:2019-05-22
摘要:牙周炎是一种全世界高度流行的口腔疾病,据统计全世界约有50%的成年人患有牙周炎。牙周炎除了造成口腔的损害之外,还可能增加不同类型全身疾病的患病风险,并加重其疾病的进程。随着牙周病与全身疾病发展的关系日益受到关注,牙周炎在NAFLD的发生、发展中的作用引起了学者们的注意。近年来有流行病学调查研究表明,牙周炎与非酒精性脂肪肝之间具有关联性,牙周炎可促进非酒精性脂肪性肝病的发生和发展。牙周炎可通过肠-肝轴,炎症介质和氧化应激等途径导致NAFLD的进展。
关键词: 牙周炎 非酒精性脂肪肝 菌群失调 肠-肝轴 炎症介质 氧化应激
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The Relationship between Periodontitis and Non-alcoholic Fatty Liver Disease
Abstract:Periodontitis is a highly prevalent oral disease throughout the world. The status shows that about 50% of adults suffer from periodontitis worldwide. Besides the oral damage, periodontitis may also increase the risk of different types of systemic diseases and aggravate the disease process. Since there is growing concern in the relationship between periodontitis and systemic diseases, the role of periodontitis in the occurrence and development of non-alcoholic fatty liver diseasehas attracted increased attention. In recent years, epidemiological studies have shown that there is an association between periodontitis and non-alcoholic fatty liver disease, and periodontitis may promote the occurrence and development of non-alcoholic fatty liver disease. Periodontitis might lead to the progress of non-alcoholic fatty liver disease through regulating gut-liver axis, inflammatory mediators and oxidative stress.
Keywords: periodontitis non-alcoholic fatty liver disease dysbacteria gut-liver axis inflammatory mediators oxidative stress
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