Self-assembly of Nano-structured Gold Particle and Its Surface-enhanced Raman Spectroscopic Application

• 1、School of Food Science and Technology, Jiangnan University, Wuxi 214122

Abstract：Based on the surface plasma enhancement characteristics of gold nanoparticles, nano-gold dotarray chip was fabricated on the glass substrate by using nano-microsphere etching technology and electrostatic adsorption principle. Firstly, gold nanospheres and gold nanocrosses were synthesized and characterized. Secondly, nano-microsphere etching technology wasused to prepare nanogold dot array chip substrates, then two nano-gold materials were self-assembled on the chip interface respectively, and the effects of different aluminum plating times on the dot size and gap distance were studied. Finally, taking the gold nanospheres array chip as an example, R6G was uesd as a Raman signal molecule to investigate its SERS enhancement performance. The results show that compared with other ultra-sensitive detection chips, the SERS enhancement factor of this chip is as high as 4.2 × 107, which has higher sensitivity and lower detection limit, and has a broad application prospect in the detection of trace substances in food.

Keywords： surface plasmon enhancement self-assembly array chip ultra-sensitive detection