Byu singa ne nsemble-avem gedt wo-fluid model, with validc losurec onditionso fin terfacialtu omenturne xchanged uet ovirtual mass force, visco us shears tressand dragf orce, amodelfo rp ressurew avep ropagation in a horizontal gas-liquid bubbly flow is proposed. Accordingt ot hes mallp erturbationt heorya nds olvablec onditiono fo eorderlinearu niform equations, ad spersione quationo fpressurew aveis in duced. The pressue wave speedc alculatedf rom the modelis compare danding oods greem entwithe xistingdata. According to the dispersion equation, the propagation and attenuation of pressure wave are investigated systemicaly. The factors affecting pressure wave, sucha sv oidf raction, pressure, wallsh ears tress, perturbationf requency, virtualm ass for ceandd ragforce, are analyzed. The result shows that the decrease in system pmmare, the increase in void fraction and the existence of wall shear stress, will cause a decre inp ressurew avesp eeda nda nIn eressein the a tenuationc oefficientin the horizontalga s-liquidb ubblyflow. Thee ffectso fp erturbstion frequency, virtual mess and drag force on pressure wave in the horizontal gas-liquid bubbly flow at low perturbation frequency are different from that at high perturbation frequency.