We present the results of high-resolution multi-proxy climate studies of the S1 palaeosol, corresponding to oxygen isotope stage (OIS) 5, from the northwestern margin of the Chinese Loess Plateau area. Here, S1 is much thicker (ca. 6-8m) than in the central Loess Plateau areas (ca. 2m), where most previous studies have been conducted. Hence, much higher-resolution stratigraphic studies are possible, yielding more insight into the temporal variations of the East Asian monsoon during MIS 5. The frequency-dependent magnetic susceptibility, as well as the concentration of secondary carbonate, is used as an indicator of the summer monsoon intensity, and the median particle size as an indicator of the winter monsoon intensity. The results suggest that the northwestern margin of the Chinese Loess Plateau experienced the strongest summer monsoon intensity in sub-stage (OISS) 5e and the weakest in OISS 5a, among the three warmer periods during stage 5. The summer monsoon was weaker in OISS 5b than in OISS 5d. A dusty interval interrupted the second warmer period (5c) and a soil-forming event interrupted the first colder period (5d). The results also suggest that the directions of changes in the intensities of summer and winter monsoons may not always have been proportionately opposite. For example, the weakest summer monsoon occurred in OISS 5a during which the winter monsoon was not the strongest. We further conclude that the winter monsoon during the last interglacial was probably driven by global ice volume fluctuations, while the summer monsoon was primarily controlled by the northern hemisphere solar insolation and was probably modified by a feedback mechanism. That is, the climatic buaering e!ect of low-latitudinal oceans may have distorted the response of the summer monsoon to insolation variations. Finally, our results do not show the degree of climatic instability comparable to that recorded in the GRIP ice core for the last interglacial (OISS 5e), even though the study area is situated in a region which has been sensitive to climatic changes.