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期刊论文
Detection of apoptotic cells in whole saliva of patients with oral remalignant and malignant lesions: A preliminary study
ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY April 2004 465～470 Cheng et al，-0001，（）：
Objective. The purpose of this study was to identify and measure apoptotic cells in whole saliva of patients with oral premalignant and malignant lesions and explore its utility as a prognostic indicator. Study design, A fluorescent TUNEL technique (APO-BrdU tunel) Modified by our lab was applied to unstimulated whole saliva from 8 healthy volunteers, 16 patients with oral leukoplakia and/or lichen lichen planus, 10 untreated and 5 treated cases with oral malignant lesion. Results, The apoptotic cells in whole saliva were detected in 4 groupls of study subjects, The apoptotic cells demonstrated morphology similar to normal exfoliated epithelial cells of oral mucosa, The fraction of apoptotic cell in treated malignant p;atients (18.18
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