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期刊论文
Response of gene expression in Saccharomyces cerevisiae to amphotericin B and nystatin measured by microarrays
Journal of Antimicrobial Chemotherapy (2002) 49, 905～915，-0001，（）：
and three genes related to cell wall biogenesis were induced, indicating that the cell membrane and cell wall were also affected by the presence of polyene antibiotics. It was observed that the pleiotropic drug resistance network in yeast cells was activated after exposure to amphotericin B, possibly contributing to the acquisition of amphotericin B resistance. Part of the gene expression alteration measured by microarray was confirmed by quantitative RT–PCR.
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