The J-integral analysis is presented for the interaction problem between a semi-infinite interface crack and subinterface matrix microcracks in dissimilar anisotropic materials. After deriving the fundamental solutions for an interface crack subjected to different loads and the fundamental solutions for an edge dislocation beneath the interface, the interaction problem is deduced to a system of singular integral equations with the aid of a superimposing technique. The integral equations are then solved numerically and a conservation law among three values of the J-integral is presented, which are induced from the interface crack tip, the microcracks and the remote field, respectively. The conservation law not only provides a necessary condition to con