提示
戴伟民
-
29浏览
-
0点赞
-
0收藏
-
0分享
-
104下载
-
0评论
-
引用
期刊论文
Molecular Design, Chemical Synthesis, Kinetic Studies, Calculations, and Biological Studies of Novel Enediynes Equipped with Triggering, Detection, and Deactivating Devices. Model Dynemicin A Epoxide and cis-Diol Systems
J. Am. Chem. Soc. 1993, 115, 7944-7953，-0001，（）：
ica gel in wet benzene. Kinetic studies used to determine the free energies of activation (AG*) for the cycloaromatization of 8 (22.6kcal/mol, 30℃) and 9 (25.7kcal/mol, 37℃) to products 32 and 33, respectively. Ab initio calculations regarding the reactivity of these systems were in agreement with the experimental findings. The isolation of compounds 8, 9, 30, and 31 provide strong support for the postulated intermediates in the dynemicin A reaction cascade. The physical, chemical, and biological profiles of the reported compounds may provide the basis for further applications in mechanistic, biological, and medical studies.
【免责声明】以下全部内容由[戴伟民]上传于[2005年03月03日 21时37分34秒]，版权归原创者所有。本文仅代表作者本人观点，与本网站无关。本网站对文中陈述、观点判断保持中立，不对所包含内容的准确性、可靠性或完整性提供任何明示或暗示的保证。请读者仅作参考，并请自行承担全部责任。
本学者其他成果
同领域成果
