-
46浏览
-
0点赞
-
0收藏
-
0分享
-
160下载
-
0评论
-
引用
期刊论文
Thermodynamic modelling of the effect of pH upon aggregation transitions in aqueous solutions of the poloxamine, T701
Thermochimica Acta 417 (2004) 201-206,-0001,():
Differential scanning calorimetry has been used to investigate the effect of pH upon the temperature interval over which aggregation occurs in aqueous solutions of the ethylene oxide (EO)/propylene oxide (PO) block co-polymeric compound tetronic T701 (molecular formula EO4PO13)2NCH2CH2N(PO13EO4)2). Self association, in this system, occurs at elevated temperatures because the PO blocks become increasingly non-polar and, as a consequence, self associate because of the hydrophobic effect. pH titration shows that the central ethylene diamine moiety is di-basic with pKa values of 3.8 and 8. Thus, in aqueous solution when the pH value is below 8 a necessary pre-condition for self association is deprotonation. A theoretical model is developed-based upon this hypothesis-which attempts to replicate, with some success, the effect of pH upon the calorimetrically observed T701 self association process.
【免责声明】以下全部内容由[董金凤]上传于[2011年06月23日 09时18分11秒],版权归原创者所有。本文仅代表作者本人观点,与本网站无关。本网站对文中陈述、观点判断保持中立,不对所包含内容的准确性、可靠性或完整性提供任何明示或暗示的保证。请读者仅作参考,并请自行承担全部责任。
本学者其他成果
同领域成果