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期刊论文

Protective Effect of Ginkgo Biloba Extract on Endothelial Cell Against Damage Induced by Oxidative Stress

杜冠华De Cheng Ren Guan-Hua Du and Jun Tian Zhang

Journal of Cardiovascular Pharmacology™ 40:809-814,-0001,():

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摘要/描述

The viability of bovine aortic endothelial cells (BAECs) treated with 0.1mM H2O2 was decreased by 39.8%, and 100 mg/l EGb761 increased the viability by 20.6%. Exposure BAECs to H2O2 for 6 min resulted in a significant elevation in the intracellular free Ca2+. Pretreatment of BAECs with 10mg/l and 100mg/l EGb761 for 10min showed a decrease in the intracellular free Ca2+, 4.5% and 20.6%, respectively. The apoptotic rate of BAECs measured by propidium iodide (PI) staining was (38.1

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