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期刊论文
Phytochemical and antiinflammatory studies on Terminalia catappa
Fitoterapia 75(2004)253-260,-0001,():
The antiinflammatory activity of Terminalia catappa leaves ethanolic extract was studied using 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced ear edema in acute and chronic models. A bioassay-oriented fractionation procedure showed that the activity concentrates in the chloroform fraction. Ursolic acid (1) and 2a, 3b, 23-trihydroxyurs-12-en-28-oic acid (2), isolated from the chloroform fraction, exhibited strongantiinflammatory activities. The results suggest that the triterpenic acids 1 and 2 are responsible for the antiinflammatory activity of T. catappa leaves.
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