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期刊论文
Directional Modifications of Resibufogenin by Mucor subtilissimus and Pseudomonas aeruginosa
Biocatalysis and Biotransformation, 2003 VOL. 21 (3). pp. 141-143,-0001,():
Directional modifications of resibufogenin 1 by Mucor subtilissimus and Pseudomonas aeruginosa were carried out. The substrate was hydroxylated at C-12 by M. subtilissimus AS 3.2454, from which a major product 12-hydroxyresibufogenin 2 was obtained. Then product 2 was dehydrogenated by P. aeruginosa AS 1.860, which resulted in a new compound 12β-hydroxy-3-keto-resibufogenin 3.
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