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In vivo study of Ti-O thin film fabricated by PIII

黄楠P. Yang a N. Huang a* Y.X. Leng a J.Y. Chen a H. Sun a J. Wang a F. Chen b P.K. Chu c

Surface and Coatings Technology 156(2002)284-288,-0001,():

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摘要/描述

Over the past decade, much attention has been paid to anti-thrombotic materials applied in artificial organs. Surface modification has shown potential to improve the anti-coagulation of blood-contacting biomedical devices and materials w1-3x. Our in vitro study of Ti-O thin films has recently shown that Ti-O thin films possess superior blood compatibility to low temperature isotropic pyrolytic carbon (LTI-carbon), w1x. In this work, we have focussed our attention onto the in vivo evaluation of Ti-O thin films fabricated by plasma immersion ion implantation (PIII). The samples of titanium coated by Ti-O thin films were implanted in dogs'hearts for 1 month. The results of the implantation showed that no thrombus was found on the surfaces of the Ti-O thin film, although the coagulation occurred on the surfaces of LTI-carbon.

版权说明:以下全部内容由黄楠上传于   2005年03月04日 17时30分31秒,版权归本人所有。

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