99mTc-TRODAT-1 SPECT study in early Parkinson's disease and essential tremor，成果详细信息-中国科技论文在线

蒋雨平

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99mTc-TRODAT-1 SPECT study in early Parkinson's disease and essential tremor

蒋雨平， J. Wang ，， Y.-P. Jiang ， X.-D. Liu ， X.-P. Chen ， L.-Q. Yang ， C.-J. Liu ， J.-D. Xiang ， H.-L. Su

Acta Meurol Scand 2005: 122: 380-385，-0001，（）：

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The clinical differentiation between early Parkinson's disease (PD) and essential tremor (ET) could be difficult, therefore, the aim of this study was to investigate 99mTc-TRODAT-1 SPECT as an applicable tool in this field Methods-99mTc-TRODAT-1 single photon emission computed tomography (SPECT) was performed in 10 healthy volunteers, 27 patients with idiopathic PD (Hoehn and Yahr 1-1.5) and 12 patients with ET, The ratio of striatal 99mTc-TRODAT-1 binding was calculated as the index of (striatum-occipital cortex)/occipital cortex. Results-Compared wit the striatal 99mTc-TRODAT-1 uptake in the ET group (0.49

关键词: Dopamine transprter ， essential tremor ， Parkinson' ， s disease ， single photon emission computed tomography ， 99mTc-TRODAT-1

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