The original ghost fluid method (GFM) developed in [13] and the modifiedGFM (MGFM) in [26] have provided a simple and yet flexible way to treat twomediumflow problems. The original GFM and MGFM make the material interface "invisible" during computations and the calculations are carried out as for a singlemedium such that its extension to multi-dimensions becomes fairly straightforward.The Runge-Kutta discontinuous Galerkin (RKDG) method for solving hyperbolic conservationlaws is a high order accurate finite element method employing the usefulfeatures from high resolution finite volume schemes, such as the exact or approximateRiemann solvers, TVD Runge-Kutta time discretizations, and limiters. In this paper,we investigate using RKDG finite element methods for two-medium flow simulationsin one and two dimensions in which the moving material interfaces is treated via nonconservativemethods based on the original GFM and MGFM. Numerical results forboth gas-gas and gas-water flows are provided to show the characteristic behaviors ofthese combinations.