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期刊论文

Synthesis and Biological Activity of 3-Methyl-1 H-pyrazole-4-4 carboxylic Ester Derivatives

李正名ZHAO Wei-Guang LI Zheng-Ming* YUAN Ping-We WANG Wen-Yan

Received July 28, 2000; accepted October 19, 2000,-0001,():

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摘要/描述

In search of novel pyrazole derivatives with bloactivity, a se-ries of 3-methyl-1 H-pyrazole-4-caboxylic ester derivatives were synthesized via a-oxoketene dithioacetals as starting ma-terial. The structures of all compounds prepared were con-firmed by 1HNMR, IR, MS and elemental analyses. Prellml-nary bioassays indicated that some compounds showed fungici-dal activity against wheat rust, phoma asparagi and antiviral activity against TMV.

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