您当前所在位置: 首页 > 学者

钱志勇

  • 15浏览

  • 0点赞

  • 0收藏

  • 0分享

  • 356下载

  • 0评论

  • 引用

期刊论文

Preparation of biodegradable polyesteramide microspheres

钱志勇Zhiyong Qian Sai Li Yi He Hailian Zhang Xiaobo Liu

Colloid Polym Sci (2004) 282: 1083-1088,-0001,():

URL:

摘要/描述

Biodegradable polyesteramide copolymer P(CL/AU) based on -caprolactone and 11-aminoundecanoic acid was synthesized by the melt polycondensation method. Polyesteramide (PEA) microspheres were prepared by a simple O/W emulsion solvent evaporation method. The effects of variations in preparation parameters (such as emulsifier concentration, polymer concentration, polymer solution adding rate, stirring rate, and whether vacuum was applied) were studied in detail. The obtained microsphere morphologies were observed using an optical microscope and via scanning electron microscopy (SEM). The particle size distribution was determined using a Malvern laser particle sizer. When the PEA microspheres were incubated in PBS saline, the particle size increased at first, and then decreased after a longer time period; the theory that this behavior was due to degradation of the microspheres was confirmed by SEM.

版权说明:以下全部内容由钱志勇上传于   2006年10月31日 01时14分19秒,版权归本人所有。

我要评论

全部评论 0

本学者其他成果

    同领域成果