A total of 377 patients with chemical burns from all over Guangdong province were admitted to the Guangzhou Red Cross Hospital during the period from January 1987 to December 2001. There were 296 males and 81 females with a male to female ratio of 3.65: 1. The mean age of the patients was 26 years. The maj ority of patients (89.2%) were in the age range of 15-60 years. Professionally, 244 patients (64.7%) were workers, of whom, 232 (95%) of patients were peasant workers. Most of the chemical burns occurred at places away from home (94.4%), especially in the working environment (67.8%). Only 20 patients (5.5 %) were inj ured at home. Chemical bums by accident and by criminal assault were 337 (88.5%) and 40 (10.5%). Strong acids (60.8%), mainly sulfuric acid. nitric acid, hydrofluoric acid, alkali (33.9%), mainly lime and sodium hydroxide were common causative agents. There was a relationship between the incidence of chemical burns and the season. with more patients in July-September and October-December. There were 215 (57.1%) patients who washed the burnsite with water immediately, but the volumes of water and time of washing were not adequate. Patients with total bum surface area (TBSA) of less than 10% comprised the maj ority of patients (72.7%), with 188 (65.7%) deep partial thickness burns. 116 (40.6%) with full thickness burns. and 60 (21%) with superficial burns. Extremities (lower limb 5 6.6% and upper limb 51.4%) were the most frequent area of injury. Ocular bums were the mo st common accompanying inj ury (14.7%). Operations of autografts and conj unctival flap were carried out on 159 (42.2%) patients. The average period of hospitalization was 22 days. Only 2 (0.7%) deaths occurred in this study. Counter measures to improve this situation must include safety productive education and professional training, use of protective clothing at work, enhancing the concept of legal responsibility, and restricting management and use of corrosive chemicals. Irrigation of the bumsite promptly with substantial volumes of water and an adequately long time will help reduce the morbidity from chemical burns.