Classical swine fever virus (CSFV) causes significant losses in the pig industry in many countries. Erns is an envelope glycoprotein of CSFV which is known to induce virus-neutralizing antibodies and protective immunity in the natural host. In this study, one recombinant baculoviruses BacSC-Erns expressing histidine-tagged Erns with the transmembrane domain (TM) and cytoplasmic domain (CTD) derived from baculovirus envelope protein gp64was constructed and its immunizing efficacywas evaluated in a mouse model. After infection, Erns was expressed and anchored on the plasma membrane of Sf-9 cells, as demonstrated by Western-blot and confocal microscopy. Immunogold electron microscopy demonstrated that the Erns glycoprotein was successfully displayed on the baculoviral envelope. Vaccine tests in animals showed that BacSC-Erns elicited significantly higher Erns antibody titers in the immunized mouse models than the control group. This demonstrates that the BacSC-Erns vaccine can be used potentially against CSFV infections. This is the first report demonstrating the potential of Erns-pseudotyped baculovirus as a CSFV vaccine.